So what's the point if it's to tolerances that can't even be reliably measured?
Once you get to those levels how you handle the part or the enviroment you are in will change parts. In many ways requiring high tolerances is bad design once you get past a certain level that isn't sustainable due to enviromental factors. Some of the best designs are the best, because they work so well without requiring high tolerance parts.
I guess it depends on the application but at some point doesn't it become irrelevant?